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Invitrogen™ LARGE Polyclonal Antibody

Goat Polyclonal Antibody
Marca: Invitrogen™ PA519292
Descripción
This antibody is predicted to react with bovine and canine based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 2,000.
The LARGE gene, which is one of the largest in the human genome, encodes a member of the N-acetylglucosaminyltransferase gene family. It encodes a glycosyltransferase which participates in glycosylation of alpha-dystroglycan, and may carry out the synthesis of glycoprotein and glycosphingolipid sugar chains. It may also be involved in the addition of a repeated disaccharide unit. Mutations in this gene cause MDC1D, a novel form of congenital muscular dystrophy with severe mental retardation and abnormal glycosylation of alpha-dystroglycan. Alternative splicing of this gene results in two transcript variants that encode the same protein.
Especificaciones
| LARGE | |
| Polyclonal | |
| Unconjugated | |
| Large1 | |
| Acetylglucosaminyltransferase-like 1A; acetylglucosaminyltransferase-like protein; Beta-1,3-glucuronyltransferase LARGE; BPFD#36; enr; eosinophil granule major basic protein 1; fg; froggy; glycosyltransferase-like 1A; Glycosyltransferase-like protein; glycosyltransferase-like protein LARGE1; glycosyltransferase-like protein LARGE1; LARGE xylosyl- and glucuronyltransferase 1; Gyltl1a; KIAA0609; large; LARGE xylosyl- and glucuronyltransferase 1; Large1; like-acetylglucosaminyltransferase; like-glycosyltransferase; MBP1; Mbp-1; MDC1D; MDDGA6; MDDGB6; mKIAA0609; myd; myodystrophy; prepro major basic protein 1; Xylosyltransferase LARGE | |
| Goat | |
| Ammonium sulfate precipitation | |
| RUO | |
| 9215 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Western Blot | |
| 0.5 mg/mL | |
| TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3 | |
| O95461 | |
| Large1 | |
| Synthetic peptide sequence (SEADVNSENLQKQ) corresponding to the internal amino acids of LARGE (aa 421-434). | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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