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  6. Epredia™ Lab Vision™ Retinoblastoma (Rb) Ab-1 Mouse Monoclonal Antibody, 200μg/mL, biotinylated, BSA and azide

Epredia™ Lab Vision™ Retinoblastoma (Rb) Ab-1 Mouse Monoclonal Antibody, 200μg/mL, biotinylated, BSA and azide

Código de producto. p-4561450 Tienda Epredia Productos
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Cantidad:
100 μL
200 μL
500 μL
1 mL
7 mL
Conjugado:
Biotin
Unconjugated
Formulario:
Concentrated
Prediluted
Concentración:
1mg/mL
200μg/mL
Prediluted
Tamaño de la unidad:
1 ml
100 microlitros
200 microlitros
500 microlitros
7 ml
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Código de producto. Cantidad Conjugado Formulario Concentración unitSize
12618876 100 μL Biotin Concentrated 200μg/mL 100 microlitros
12628876 500 μL Biotin Concentrated 200μg/mL 500 microlitros
12648876 100 μL Unconjugated Concentrated 200μg/mL 100 microlitros
12658876 100 μL Unconjugated Concentrated 1mg/mL 100 microlitros
12678876 200 μL Unconjugated Concentrated 1mg/mL 200 microlitros
12668876 500 μL Unconjugated Concentrated 200μg/mL 500 microlitros
12638876 1 mL Unconjugated Concentrated 200μg/mL 1 ml
12608886 7 mL Unconjugated Prediluted Prediluted 7 ml
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Product Code. 12618876 Supplier Epredia™ Supplier No. MS107B0

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Description

Provide accurate, reproducible results with the Epredia™ Retinoblastoma (Rb) Ab-1, Mouse Monoclonal Antibody.

Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA. It is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the RB gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.

Host Species: Mouse

Clone: 1F8; same as Rb1

Isotype: IgG1

Species Reactivity: Human. Does not react with mouse and rat. Others not known.

Epitope: aa 703-722

Immunogen: Recombinant human Rb protein

Molecular Weight: 105kDa

Positive Control: Ls174T, HT29, HUVEC cells; Normal colon, Breast CA and colon CA

Cellular Localization: Nuclear Ab-1 specifically stains the nuclei of BT-20 cells and primary human foreskin fibroblast (HFF) cells. It reacts with hyperphosphorylated and un (under) phosphorylated form of Rb protein. It shows no cross reaction with p107 and p130.

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Native and denatured)
  • Flow Cytometry

Note:

USA: RUO; Int'l: RUO

TRUSTED_SUSTAINABILITY

Specifications

Antígeno Retinoblastoma (Rb) Ab-1
Aplicaciones Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clasificación Monoclonal
Clon 1F8; same as Rb1
Concentración 200μg/mL
Conjugado Biotin
Especie del huésped Mouse
Inmunógeno Recombinant human Rb protein
Cantidad 100 μL
Estado normativo RUO
Disciplina de investigación Cancer and Tumor Biology
Primario o secundario Primary
Especies diana Human
Formulario Concentrated
Isotype IgG1
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