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Invitrogen™ KHDRBS3 Polyclonal Antibody
Rabbit Polyclonal Antibody
Marca: Invitrogen™ PA551372
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Descripción
Immunogen sequence: ADVPVVRGKP TLRTRGVPAP AITRGRGGVT ARPVGVVVPR GTPTPRGVLS TRGPVSRGRG LLTPRARGVP PTGYRPPPPP PTQETYGEYD YDDGYGTAYD EQSYDS Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 93%.
As a RNA-binding protein, KHDRBS3 plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. KHDRBS3 may play a role as a negative regulator of cell growth. It inhibits cell proliferation and involved in splice site selection of vascular endothelial growth factor. It induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. RNA-binding abilities are down-regulated by tyrosine kinase PTK6. It also involved in post-transcriptional regulation of HIV-1 gene expression.
Especificaciones
| KHDRBS3 | |
| Polyclonal | |
| Unconjugated | |
| Khdrbs3 | |
| Etle; etoile; etoile, Sam68-like protein SLM-2; KH domain containing, RNA binding, signal transduction associated 3; KH domain-containing, RNA-binding, signal transduction-associated protein 3; KH RNA binding domain containing, signal transduction associated 3; KHDRBS3; RNA-binding protein Etoile; RNA-binding protein T-Star; rSLM-2; SALP; Sam68-like mammalian protein 2; Sam68-like phosphotyrosine protein; Sam68-like phosphotyrosine protein, T-STAR; SLM2; SLM-2; TSTAR; T-STAR | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 10656 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin) | |
| 0.1 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| O75525 | |
| Khdrbs3 | |
| Recombinant protein corresponding to Human KHDRBS3. Recombinant protein control fragment (Product #RP-93686). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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