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Invitrogen™ KCNQ2 Polyclonal Antibody
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Código de producto. 15897083
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Cantidad:
100 μL
Tamaño de la unidad:
100 microlitros
Código de producto. Cantidad unitSize
15897083 100 μL 100 microlitros
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Código de producto. 15897083

Marca: Invitrogen™ PA568676

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Rabbit Polyclonal Antibody

This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 93%.

KCNQs are members of the voltage-dependent non-inactivating potassium channel family. Currently there are five known KNCQs (KCNQ1-5) found in the central nervous system and KNCQ2 and 3 have demonstrated their importance in M-current activation. Studies have shown that KCNQ2 and KCNQ3 form heteromultimers that, when formed, substantially increase the M-current. Inhibition of M-current controls neuron excitability throughout the nervous system as well as the responsiveness to synaptic inputs. Genetic mutations in these proteins have been linked to disorders such as benign familial neonatal convulsions (BFNC), deafness, neuropathic pain and epilepsy.
TRUSTED_SUSTAINABILITY

Especificaciones

Antígeno KCNQ2
Aplicaciones Western Blot
Clasificación Polyclonal
Concentración 0.5 mg/mL
Conjugado Unconjugated
Formulación PBS with 2% sucrose and 0.09% sodium azide
génica KCNQ2
N.º de referencia del gen Q9Z351
Alias de gen BFNC; EBN; EBN1; ENB1; HNSPC; KCNA11; KCNQ2; KQT like 2; KQT2; KQT-like 2; KV7.2; KVEBN1; mKQT2.3; mKQT2.4; neuroblastoma-specific potassium channel subunit alpha KvLQT2; Nmf134; potassium channel subunit alpha KvLQT2; potassium channel, voltage gated KQT-like subfamily Q, member 2; potassium channel, voltage-gated KQT-like subfamily Q, member 2; potassium voltage-gated channel KQT-like subfamily member 2.3; potassium voltage-gated channel KQT-like subfamily member 2.4; potassium voltage-gated channel subfamily KQT member 2; potassium voltage-gated channel subfamily Q member 2; potassium voltage-gated channel, KQT-like subfamily, member 2; potassium voltage-gated channel, subfamily Q, member 2; voltage-gated potassium channel subunit Kv7.2
Símbolos de los genes KCNQ2
Especie del huésped Rabbit
Inmunógeno synthetic peptide directed towards the middle region of human KCNQ2 (aa 182-231).
Método de purificación Affinity Chromatography
Cantidad 100 μL
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 16536
Especies diana Mouse
Contenido y almacenamiento -20°C, Avoid Freeze/Thaw Cycles
Tipo de producto Antibody
Formulario Liquid
Isotype IgG
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