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Invitrogen™ KCNQ2 Polyclonal Antibody

Descripción
This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 93%.
KCNQs are members of the voltage-dependent non-inactivating potassium channel family. Currently there are five known KNCQs (KCNQ1-5) found in the central nervous system and KNCQ2 and 3 have demonstrated their importance in M-current activation. Studies have shown that KCNQ2 and KCNQ3 form heteromultimers that, when formed, substantially increase the M-current. Inhibition of M-current controls neuron excitability throughout the nervous system as well as the responsiveness to synaptic inputs. Genetic mutations in these proteins have been linked to disorders such as benign familial neonatal convulsions (BFNC), deafness, neuropathic pain and epilepsy.
Especificaciones
Especificaciones
| Antígeno | KCNQ2 |
| Aplicaciones | Western Blot |
| Clasificación | Polyclonal |
| Concentración | 0.5 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 2% sucrose and 0.09% sodium azide |
| génica | KCNQ2 |
| N.º de referencia del gen | Q9Z351 |
| Alias de gen | BFNC; EBN; EBN1; ENB1; HNSPC; KCNA11; KCNQ2; KQT like 2; KQT2; KQT-like 2; KV7.2; KVEBN1; mKQT2.3; mKQT2.4; neuroblastoma-specific potassium channel subunit alpha KvLQT2; Nmf134; potassium channel subunit alpha KvLQT2; potassium channel, voltage gated KQT-like subfamily Q, member 2; potassium channel, voltage-gated KQT-like subfamily Q, member 2; potassium voltage-gated channel KQT-like subfamily member 2.3; potassium voltage-gated channel KQT-like subfamily member 2.4; potassium voltage-gated channel subfamily KQT member 2; potassium voltage-gated channel subfamily Q member 2; potassium voltage-gated channel, KQT-like subfamily, member 2; potassium voltage-gated channel, subfamily Q, member 2; voltage-gated potassium channel subunit Kv7.2 |
| Símbolos de los genes | KCNQ2 |
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Título del producto
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