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Invitrogen™ KCC2 Monoclonal Antibody (N1/12), PE

Mouse Monoclonal Antibody
Marca: Invitrogen™ MA545498
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Descripción
1 μg/mL of MA5-45498 was sufficient for detection of KCC2 in 10 μg of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 140kDa. This antibody was formerly sold as clone S1-12.
Mediates electroneutral potassium-chloride cotransport in mature neurons. Transport occurs under isotonic conditions, but is activated 20-fold by cell swelling. Important for Cl(-) homeostasis in neurons.
Especificaciones
| KCC2 | |
| Monoclonal | |
| 1 mg/mL | |
| 2.48mM MES, 95.64mM phosphate with 0.5M EDTA and no preservative; pH 7.4 | |
| Q63633, Q91V14, Q9H2X9 | |
| SLC12A5 | |
| Fusion protein amino acids 932-1043 corresponding to rat KCC2. | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG2a |
| Immunohistochemistry, Immunoprecipitation, Western Blot, Immunocytochemistry | |
| N1/12 | |
| PE | |
| SLC12A5 | |
| EIEE34; EIG14; Electroneutral potassium-chloride cotransporter 2; erythroid K-Cl cotransporter 2; furosemide-sensitive K-Cl cotransporter; hKCC2; KCC 2; Kcc2; KCC2a variant 1; KCC2a-S25 variant 1; KCC2b variant 2; K-Cl cotransporter 2; KIAA1176; mKCC2; mKIAA1176; neuronal K-Cl cotransporter; neuronal-specific K-Cl cotransporter; rKCC2; S12A5; SLC12A5; solute carrier family 12 (potassium/chloride transporter), member 5; solute carrier family 12 (potassium-chloride transporter), member 5; solute carrier family 12 member 5; solute carrier family 12, (potassium-chloride transporter) member 5; solute carrier family 12, member 5 | |
| Mouse | |
| Protein G | |
| RUO | |
| 171373, 57138, 57468 | |
| 4°C | |
| Liquid |
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