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Invitrogen™ JIP2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Marca: Invitrogen™ PA529245
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Descripción
Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji, mouse brain. Predicted reactivity: Mouse (98%), Bovine (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene is closely related to MAPK8IP1/IB1/JIP-1, a scaffold protein that is involved in the c-Jun amino-terminal kinase signaling pathway. This protein is expressed in brain and pancreatic cells. It has been shown to interact with, and regulate the activity of MAPK8/JNK1, and MAP2K7/MKK7 kinases. This protein thus is thought to function as a regulator of signal transduction by protein kinase cascade in brain and pancreatic beta-cells. Alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene.
Especificaciones
| JIP2 | |
| Polyclonal | |
| Unconjugated | |
| MAPK8IP2 | |
| 3230402N03Rik; AI847694; AW049958; C-Jun-amino-terminal kinase-interacting protein 2; homologous to mouse JIP-1; IB 2; Ib2; IB-2; Islet brain 2; islet-brain 2; islet-brain-2; JIP 2; JIP2; JIP-2; JNK MAP kinase scaffold protein 2; JNK MAP kinase scaffold protein JIP2; JNK-interacting protein 2; Mapk8ip2; mitogen activated protein kinase 8 interacting protein 2; mitogen-activated protein kinase 8 interacting protein 2; mitogen-activated protein kinase 8-interacting protein 2; PRKM8IPL; R75148; si:dkey-180h12.2; si:dkey-181m21.1 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 23542, 60597 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Western Blot, Immunocytochemistry | |
| 1 mg/mL | |
| 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7 | |
| Q13387, Q9ERE9 | |
| MAPK8IP2 | |
| Recombinant protein encompassing a sequence within the C-terminus region of human JIP2. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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