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Invitrogen™ JIP2 Polyclonal Antibody
Descripción
Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji, mouse brain. Predicted reactivity: Mouse (98%), Bovine (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene is closely related to MAPK8IP1/IB1/JIP-1, a scaffold protein that is involved in the c-Jun amino-terminal kinase signaling pathway. This protein is expressed in brain and pancreatic cells. It has been shown to interact with, and regulate the activity of MAPK8/JNK1, and MAP2K7/MKK7 kinases. This protein thus is thought to function as a regulator of signal transduction by protein kinase cascade in brain and pancreatic beta-cells. Alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene.
Especificaciones
Especificaciones
| Antígeno | JIP2 |
| Aplicaciones | Western Blot, Immunocytochemistry |
| Clasificación | Polyclonal |
| Concentración | 1 mg/mL |
| Conjugado | Unconjugated |
| Formulación | 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7 |
| génica | MAPK8IP2 |
| N.º de referencia del gen | Q13387, Q9ERE9 |
| Alias de gen | 3230402N03Rik; AI847694; AW049958; C-Jun-amino-terminal kinase-interacting protein 2; homologous to mouse JIP-1; IB 2; Ib2; IB-2; Islet brain 2; islet-brain 2; islet-brain-2; JIP 2; JIP2; JIP-2; JNK MAP kinase scaffold protein 2; JNK MAP kinase scaffold protein JIP2; JNK-interacting protein 2; Mapk8ip2; mitogen activated protein kinase 8 interacting protein 2; mitogen-activated protein kinase 8 interacting protein 2; mitogen-activated protein kinase 8-interacting protein 2; PRKM8IPL; R75148; si:dkey-180h12.2; si:dkey-181m21.1 |
| Símbolos de los genes | MAPK8IP2 |
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Título del producto
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