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Invitrogen™ IRGC Polyclonal Antibody

Código de producto. 12888932
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Cantidad:
100 μg
Tamaño de la unidad:
100 microgramos
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Código de producto. Cantidad unitSize
12888932 100 μg 100 microgramos
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Código de producto. 12888932 Proveedor Invitrogen™ N.º de proveedor PA520790

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Descripción

Rabbit Polyclonal Antibody

A suggested positive control is mouse brain tissue lysate. PA5-20790 can be used with blocking peptide PEP-0904.

Immunity-related GTPases (IRG) (also known as p47 GTPases) are a family of GTPase proteins found in vertebrates, which play critical roles in mediating innate resistance to intracellular pathogens. IRG genes have been found in a number of mammals and lower species including mice, rats, zebrafish and humans. Most of the mouse genes contain interferon-stimulated response elements which mediate transcriptional activation by IFNs. In humans, only two IRG genes have been found: human IRGC encodes a full-length IRG protein that, like the mouse homologue, is constitutively expressed in testis, while human IRGM encodes a considerably truncated protein that is constitutively expressed in cultured cells including some macrophage cell lines. As the two human genes IRGC and IRGM are not subject to IFN control, it has been suggested that the host resistance mechanism supported by IRG proteins in the mouse is lacking in humans.
TRUSTED_SUSTAINABILITY

Especificaciones

Antígeno IRGC
Aplicaciones Western Blot, Immunocytochemistry
Clasificación Polyclonal
Concentración 1 mg/mL
Conjugado Unconjugated
Formulación PBS with 0.02% sodium azide
génica Irgc
N.º de referencia del gen Q6AYF9, Q6NXR0
Alias de gen CINEMA; cinema 1; F630044M05Rik; Gm1102; Gm474; IFGGE; Iigp5; immunity related GTPase cinema; immunity-related GTPase cinema 1; immunity-related GTPase family, cinema; immunity-related GTPase family, cinema 1; interferon inducible GTPase 5; interferon inducible GTPase family member 5; interferon-gamma-inducible GTPase IFGGE protein; interferon-inducible GTPase 5; Irgc; IRGC1; R30953_1; RGD1311107
Símbolos de los genes Irgc, Irgc1
Especie del huésped Rabbit
Inmunógeno a 12 amino acid peptide near the carboxy terminus of human IRGC.
Método de purificación Antigen affinity chromatography
Cantidad 100 μg
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 210145, 308428, 56269
Especies diana Human, Mouse, Rat
Contenido y almacenamiento Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
Tipo de producto Antibody
Formulario Liquid
Isotype IgG
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