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Invitrogen™ ING3 Polyclonal Antibody
Rabbit Polyclonal Antibody
Marca: Invitrogen™ PA5111622
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Descripción
Immunogen sequence: KLDQELAKFK MELEADNAGI TEILERRSLE LDTPSQPVNN HHAHSHTPVE KRKYNPTSHH TTTDHIPEKK FKSEALLSTL T Highest antigen sequence indentity to the following orthologs: Mouse - 95%, Rat - 98%.
The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed.
Especificaciones
| ING3 | |
| Polyclonal | |
| Unconjugated | |
| ING3 | |
| 1300013A07Rik; Eaf 4; Eaf4; FLJ20089; HSPC301; ING 2; ING 3; ING2; ING3; ing3 protein; inhibitor of growth family member 3; inhibitor of growth family, member 3; inhibitor of growth protein 3; inhibitor of growth protein 3-like protein; MEAF4; p47 p47 ING3; p47 regulator protein; p47ING3; p47ING3 protein; zgc:56327 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 54556 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin) | |
| 0.2 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q9NXR8 | |
| ING3 | |
| Recombinant Protein corresonding to Human ING3. Recombinant protein control fragment (Product #RP-103655). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
Título del producto
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