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Invitrogen™ IL24 Monoclonal Antibody (OTI3C5)
Mouse Monoclonal Antibody
Marca: Invitrogen™ MA527140
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Descripción
IL24 Monoclonal Antibody for Western Blot, IHC (P)
Interleukin 24 (IL-24)/melanoma differentiation-associated gene-7 (mda-7) encodes a secreted protein that exhibits significant homology to the interleukin 10 (IL-10) family of cytokines. The human IL-24 is secreted by activated peripheral blood mononuclear cells and binds two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2 resulting in the activation of JAK/STAT signaling pathways. Mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner.
Especificaciones
| IL24 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| Q13007 | |
| IL24 | |
| Human recombinant protein fragment corresponding to amino acids 52-206 of IL24 produced in E.coli. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Immunohistochemistry (Paraffin), Western Blot | |
| OTI3C5 | |
| Unconjugated | |
| IL24 | |
| C49A; Cytokine-like protein Mob-5; FISP; IL 24; IL10B; Il24; IL-24; IL-4-induced secreted protein; Interleukin; interleukin 24; interleukin-24; Mda7; MDA-7; melanocyte-associated Mda-7; melanoma differentiation-associated gene 7 protein; Mob5; ST16; suppression of tumorigenicity 16 (melanoma differentiation); Suppression of tumorigenicity 16 protein; Th2-specific cytokine FISP | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 11009 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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