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Invitrogen™ IL12RB2 Polyclonal Antibody

Descripción
The antibody detects endogenous levels of total IL12RB2 protein.
The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense.
Especificaciones
Especificaciones
| Antígeno | IL12RB2 |
| Aplicaciones | Immunohistochemistry (Paraffin) |
| Clasificación | Polyclonal |
| Concentración | 0.5 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 40% glycerol and 0.05% sodium azide; pH 7.4 |
| génica | IL12RB2 |
| N.º de referencia del gen | Q99665 |
| Alias de gen | A930027I18Rik; Ifnm; IL-12 receptor subunit beta-2; IL-12R subunit beta-2; Il12rb2; IL-12RB2; IL-12R-beta-2; interferon response to microorganisms; interleukin 12 receptor subunit beta 2; interleukin 12 receptor, beta 2; interleukin-12 receptor beta-2 chain; interleukin-12 receptor subunit beta-2; RP11-102M16.1 |
| Símbolos de los genes | IL12RB2 |
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Título del producto
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