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Invitrogen™ IL-3 Monoclonal Antibody (4815)
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Código de producto. 15583382
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Cantidad:
500 μg
Tamaño de la unidad:
500 microgramos
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15583382 500 μg 500 microgramos
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Código de producto. 15583382 Proveedor Invitrogen™ N.º de proveedor MA523695

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Descripción

Mouse Monoclonal Antibody

In sandwich ELISAs, no significant cross-reactivity or interference with recombinant human (rh) IL-1 alpha, rhIL-1 beta, recombinant mouse (rm) IL-1 beta, rhIL-2, rhIL-3 R alpha, rhIL-3 R beta, rmIL-3, rhIL-4, rmIL-4, rmIL-5, rhIL-6, rmIL-6, rhIL-7, rmIL-7, rhIL-8, bovine FGF acidic, bovine FGF basic, rhG-CSF, rhGM-CSF, rmGM-CSF, rhLIF, hPDGF, porcine PDGF, human TGF- beta 1, porcine TGF- beta 1, rhTGF- beta 1, porcine TGF- beta 2, porcine TGF- beta 1.2, rhTNF-alpha, or rhTNF-beta was observed. This antibody does not neutralize the biological activity of rmIL-3. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.

Interleukin 3 (IL-3), also called Mast Cell Growth Factor (MCGF), Multi-Colony Stimulating Factor (multi-CSF), or Eosinophil-CSF (E-CSF), is produced by activated T cells, mast cells and eosinophils. IL-3 is a hematopoietic growth factor that stimulates colony formation of erythroid, megakaryocyte, neutrophil, eosinophil, basophil, mast cell and monocytic lineages. Most of these functions are enhanced or dependent on co-stimulation with other cytokines. Human and mouse IL-3 share only 29% sequence identity at the amino acid level. The bioactivity of IL-3 is highly species specific. For example, human IL-3 has no activity on mouse cells. IL-3 is a potent growth promoting cytokine. IL-3 is capable of supporting the proliferation of a broad range of hematopoietic cell types, and is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. IL-3 has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders.
TRUSTED_SUSTAINABILITY

Especificaciones

Antígeno IL-3
Aplicaciones ELISA, Neutralization
Clasificación Monoclonal
Clon 4815
Concentración 0.5 mg/mL
Conjugado Unconjugated
Formulación PBS with 5% trehalose and No Preservative
génica IL3
N.º de referencia del gen P08700
Alias de gen BP/BPA; BPA; Colony stimulating factor multiple; colony-stimulating factor, multiple; Csfmu; Eo-CSF; HCGF; hematopoietic growth factor; Il3; Il-3; ILN; Interleukin; interleukin 3; Interleukin 3 (colony stimulating factor; Interleukin3; interleukin-3; Mast cell growth factor; mast-cell growth factor; MCGF; MGC79398; MGC79399; MGF; Multi CSF; MULTI-CSF; Multilineage colony stimulating factor; multilineage-colony-stimulating factor; multiple); multipotential colony-stimulating factor; P cell stimulating factor; P-cell stimulating factor; P-cell-stimulating factor; PCSA; PSF
Símbolos de los genes IL3
Especie del huésped Mouse
Inmunógeno E. coli-derived recombinant human IL-3 Ala20-Phe152.
Método de purificación Protein A/G
Cantidad 500 μg
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 3562
Especies diana Human
Contenido y almacenamiento -20°C, Avoid Freeze/Thaw Cycles
Tipo de producto Antibody
Formulario Lyophilized
Isotype IgG1
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