missing translation for 'onlineSavingsMsg'
Learn More

Invitrogen™ IL-18BP Human ELISA Kit

Sandwich ELISA Kit

Marca:  Invitrogen™ EHIL18BPX10

2870.95 EUR hasta el 2023-03-27
Use el código promocional "20585" para aplicar la oferta.

Detalles adicionales : Peso : 2.50000kg

 Ver más versiones de este producto

Código de producto. 17824210

  • 4285.00€ / paquete de 10

Fecha estimada de envío: 27-04-2023
para ver el stock
Añadir a la cesta



The Human Interleukin 18 Binding Protein (Hu IL-18BP) ELISA quantitates Hu IL-18BP in human serum, plasma, or cell culture medium. The assay will exclusively recognize both natural and recombinant Hu IL-18BP. Principle of the method The Human IL-18BP solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples, standards, or controls are then added into these wells and bind to the immobilized (capture) antibody. The sandwich is formed by the addition of the second (detector) antibody, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal. The intensity of this signal is directly proportional to the concentration of target present in the original specimen. Rigorous validation Each manufactured lot of this ELISA kit is quality tested for criteria such as sensitivity, specificity, precision, and lot-to-lot consistency. See manual for more information on validation.

IL-18 (also referred to as IL-1γ) has been shown to augment the secretion of IFN-γ from T lymphocytes and to increase NK cell activity in spleen cells. IL-18 exhibits 19% and 12% identity with IL-1α and IL-β, respectively, over the twelve β-strands of the β-trefoil fold domain, which is a signature feature of the IL-1 family. The unusual leader sequence of IL-18 may be analogous to the IL-1β pro-domain, which must be cleaved by the serine protease ICE for optimal secretion and biological activity. IL-18, which was originally described as IGIF (IFN-γ-inducing factor), IL-18 is induced in mouse liver subsequent to challenge with lipopolysaccharide (LPS). IL-18 binding protein (IL-18BP) functions as an inhibitor of the early Th1 response by binding to IL-18 and inhibiting IFN-γ production. IL-18BP is a member of the immunoglobulin superfamily and shares some homology to IL-1RII.


20 pg/mL
Solid-phase sandwich ELISA
10 x 96 assays
ELISA, Protein Assays, Protein Biology, Cancer Biology, Immunology, Neuroscience, Neurobiology, Protein Detection, Protein Analysis
Pre-coated 96 well plate, Assay Diluent concentrate, Adhesive Plate Covers, Wash Buffer, Chromogen, Stop Solution, Biotinylated Detection Antibody, SAV-HRP, Standard
10 x 96 Tests
Signal Transduction
2°C to 8°C
4 hr. 45 min.
24.69 to 18,000 pg/mL
20 pg/mL to 18000 pg/mL
Other Proteins
This ELISA kit shows no cross-reactivity with any of the cytokines tested: Human Angiogenin, BDNF, BLC, ENA-78, FGF-4, IL-1 alpha, IL-1 beta, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-11, IL-12 p70, IL-12 p40, IL-13, IL-15, IL-309, IP-10, G-CSF, GM-CSF, IFN-gamma, Leptin (OB), MCP-1, MCP-2, MCP-3, MDC, MIP-1 alpha, MIP-1 beta, MIP-1 delta, PARC, PDGF, RANTES, SCF, TARC, TGF-beta, TIMP-1, TIMP-2, TNF-alpha, TNF-beta, TPO, VEGF.
Colorimetric Microplate Reader
Plasma, 33 μL; Serum, 33 μL; Supernatant, 100 μL
1 hr. 20 min.


Ofertas especiales

Ofertas especiales