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Invitrogen™ IL-18BP Human ELISA Kit

Sandwich ELISA Kit

654.00€ - 4715.00€

Especificaciones

Número de acceso O95998
Sensibilidad del ensayo 20 pg
ensayo ELISA sandwich de fase sólida
Conjugado Biotina
Tipo de producto Kit de ELISA
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Productos 3
Código de producto Marca Cantidad Precio Cantidad y disponibilidad  
Código de producto Marca Cantidad Precio Cantidad y disponibilidad  
15445033
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Invitrogen™
EHIL18BP
96 pruebas
654.00€
1 set
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Fecha estimada de envío: 23-04-2024
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17824210
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Invitrogen™
EHIL18BPX10
10 × 96 pruebas
4715.00€
paquete de 10
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Fecha estimada de envío: 02-05-2024
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17155479
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Invitrogen™
EHIL18BPX5
5 × 96 pruebas
2635.00€
cada uno
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Fecha estimada de envío: 30-04-2024
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Descripción

Descripción

The Human Interleukin 18 Binding Protein (Hu IL-18BP) ELISA quantitates Hu IL-18BP in human serum, plasma, or cell culture medium. The assay will exclusively recognize both natural and recombinant Hu IL-18BP. Principle of the method The Human IL-18BP solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples, standards, or controls are then added into these wells and bind to the immobilized (capture) antibody. The sandwich is formed by the addition of the second (detector) antibody, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal. The intensity of this signal is directly proportional to the concentration of target present in the original specimen. Rigorous validation Each manufactured lot of this ELISA kit is quality tested for criteria such as sensitivity, specificity, precision, and lot-to-lot consistency. See manual for more information on validation.

IL-18 (also referred to as IL-1γ) has been shown to augment the secretion of IFN-γ from T lymphocytes and to increase NK cell activity in spleen cells. IL-18 exhibits 19% and 12% identity with IL-1α and IL-β, respectively, over the twelve β-strands of the β-trefoil fold domain, which is a signature feature of the IL-1 family. The unusual leader sequence of IL-18 may be analogous to the IL-1β pro-domain, which must be cleaved by the serine protease ICE for optimal secretion and biological activity. IL-18, which was originally described as IGIF (IFN-γ-inducing factor), IL-18 is induced in mouse liver subsequent to challenge with lipopolysaccharide (LPS). IL-18 binding protein (IL-18BP) functions as an inhibitor of the early Th1 response by binding to IL-18 and inhibiting IFN-γ production. IL-18BP is a member of the immunoglobulin superfamily and shares some homology to IL-1RII.
Especificaciones

Especificaciones

O95998
ELISA sandwich de fase sólida
Kit de ELISA
Plasma, Sobrenadante, Suero
Humano
Lector de microplacas colorimétrico
IL18BP
< 10 %
RUO
De 2 °C a 8 °C
Humano
4 h 45 min
20 pg
Biotina
Otras proteínas
Este kit de ELISA no muestra reactividad cruzada con ninguna de las citocinas analizadas: Angiogenina humana, BDNF, BLC, ENA-78, FGF-4, IL-1 alfa, IL-1 beta, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-11, IL-12 p70, IL-12 p40, IL-13, IL-15, IL-309, IP-10, G-CSF, GM-CSF, IFN-gamma, leptina (OB), MCP-1, MCP-2, MCP-3, MDC, MIP-1 alfa, MIP-1 beta, MIP-1 delta, PARC, PDGF, RANTES, SCF, TARC, TGF-beta, TIMP-1, TIMP-2, TNF-alfa, TNF-beta, TPO, VEGF.
ELISA, ensayos de proteínas, biología de proteínas, biología del cáncer, inmunología, neurociencia, neurología, detección de proteínas, análisis de proteínas
10068
< 12 %
Peroxidasa de rábano picante (HRP)
Transducción de señal
IL18BPa
1 h 20 min
Videos
SDS
Documentos

Documentos

Product Certifications