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Invitrogen™ IKK alpha Polyclonal Antibody
Rabbit Polyclonal Antibody
Marca: Invitrogen™ PA585745
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Descripción
Keep as concentrated solution. Positive Control: HeLa, Jurkat, Raji, HCI-H929, K562, THP-1, HL-60. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
CHUK (IKK alpha) is a serine/threonine kinase involved in signal transduction and cellular communication. It belongs to the cytokine activated protein complex that is an inhibitor of the NF-kappa B complex. IKK alpha along with IKK beta and a regulatory protein NEMO (IKK gamma) phosphorylates IkB proteins which targets the later for ubiquitin mediated degradation. It is involved with several cellular processes with extensive studies on its role in inflammation and cell survival.
Especificaciones
| IKK alpha | |
| Polyclonal | |
| Unconjugated | |
| CHUK | |
| AI256658; CHUK; Chuk1; component of inhibitor of nuclear factor kappa B kinase complex; conserved helix-loop-helix ubiquitous kinase; EC 2.7.11.10; Fbx24; Fbxo24; FLJ40509; I kappa B kinase 1; i kappa-B kinase alpha; ikappaB kinase; I-kappa-B kinase 1; I-kappa-B kinase 2; IkappaB kinase alpha; I-kappa-B kinase alpha; I-kappa-B kinase-alpha; IkB kinase alpha subunit; IkB kinase-alpha; ikBKA; IKBKB; IKK alpha; IKK1; IKK2; Ikka; IKK-A; IKK-a kinase; IKK-alpha; IKKB; IKK-B; IKK-beta; Inhibitor of nuclear factor kappa-B kinase subunit alpha; kinase beta; MGC131801; NFKBIKA; NFKBIKB; Nuclear factor NFkappaB inhibitor kinase alpha; Nuclear factor NF-kappa-B inhibitor kinase alpha; TCF16; TCF-16; Transcription factor 16 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 1147 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Western Blot | |
| 1.42 mg/mL | |
| PBS with 20% glycerol and 0.025% ProClin 300; pH 7 | |
| O15111 | |
| CHUK | |
| Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human IKK alpha. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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