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Invitrogen™ IGF1R alpha Polyclonal Antibody
Rabbit Polyclonal Antibody
Marca: Invitrogen™ PA514677
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Descripción
This antibody is predicted to react with mouse and rat based on sequence homology.
IGF1R (Insulin-like Growth Factor1 Receptor) is a receptor tyrosine kinase that mediates actions of insulin-like growth factor 1 (IFG1). It binds IGF1 with high affinity and IGF2/insulin with lower affinity. Activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation and survial of malignant cells. Ligand binding activates the receptor kinase and leads to receptor autophosphorylation and tyrosines phosphorylation of multiple substrates that function as signaling adapter proteins.
Especificaciones
| IGF1R alpha | |
| Polyclonal | |
| Unconjugated | |
| Igf1r | |
| A330103N21Rik; CD221; D930020L01; hyft; IGF-1 receptor; Igf1r; IGF-1R; IGF-I receptor; IGFIR; IGFIRC; IGFR; Igfr1; insulin like growth factor 1 receptor; insulin-like growth factor 1 receptor; Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain; insulin-like growth factor 1 receptor beta subunit; insulin-like growth factor I receptor; insulin-like growth factor receptor 1; insulin-like growth factor-I receptor; insulin-like growth factor-I receptor precursor; JTK13; line 186; soluble IGF1R variant 1; soluble IGF1R variant 2 | |
| Rabbit | |
| Ammonium sulfate precipitation, Size-exclusion - Dialysis | |
| RUO | |
| 3480 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 0.5 mg/mL | |
| PBS with 0.09% sodium azide; pH 7.4 | |
| P08069 | |
| Igf1r | |
| KLH conjugated synthetic peptide between 19-51 amino acids from the N-terminal region of human IGF1 Receptor (IGF1R). | |
| 400 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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