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Invitrogen™ IBSP Polyclonal Antibody
Rabbit Polyclonal Antibody
Marca: Invitrogen™ PA550633
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Beschreibung
The antibody detects endogenous levels of total IBSP protein.
The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor.
Spezifikation
| IBSP | |
| Polyclonal | |
| Unconjugated | |
| Ibsp | |
| BNSP; Bone sialoprotein 2; bone sialoprotein II; Bsp; BSP II; Bsp2; BSPII; BSP-II; Cell-binding sialoprotein; IBSP; integrin binding sialoprotein; integrin-binding sialoprotein; SP-II | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 3381 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 1.4 mg/mL | |
| PBS with 40% glycerol and 0.05% sodium azide; pH 7.4 | |
| P21815 | |
| Ibsp | |
| Synthetic peptide corresponding to a region derived from internal residues of human integrin-binding sialoprotein. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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