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Invitrogen™ I-Ek Monoclonal Antibody (14-4-4S)
Mouse Monoclonal Antibody
Marca: Invitrogen™ MA170066
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Descripción
MA1-70066 detects I-Ek in mouse samples. MA1-70066 has been successfully used in flow cytometry and cytotoxicity studies. The MA1-70066 immunogen is C3H.
MHC (major histocompatibility complex) class II molecules are transmembrane glycoproteins expressed on the surface of professional antigen-presenting cells, such as macrophages, dendritic cells and B cells. Before their exposition on the cell surface, the MHC class II molecules react with endocytosed exogenous antigens, which are then presented to the T cells. The antigen-binding grove between MHC class II alpha and beta chain is open at both ends and is 15-24 amino acid residues long. HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.
Especificaciones
| I-Ek | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 0.02% sodium azide | |
| P04230, P14439 | |
| H2-Ea-ps, H2-Eb1 | |
| C3H. | |
| 250 μg | |
| Primary | |
| Mouse | |
| Antibody | |
| IgG2a |
| Cytotoxicity Assay, Flow Cytometry | |
| 14-4-4S | |
| Unconjugated | |
| H2-Eb1 | |
| AI323765; cell surface glycoprotein; E-alpha-f; H-2 class II histocompatibility antigen, E-D alpha chain; H-2 class II histocompatibility antigen, E-K alpha chain; H-2 class II histocompatibility antigen, E-U alpha chain; H-2 class II histocompatibility antigen, I-E beta chain; H-2Ea; H2-Ea; H2-Ea-ps; H2Eb; H-2Eb; H2-Eb1; H2-IE-alpha; histocompatibility 2, class II antigen E alpha; histocompatibility 2, class II antigen E alpha, pseudogene; histocompatibility 2, class II antigen E beta; Ia3; Ia-3; Ia4; Ia-4; I-E alpha MHC class II; I-E beta MHC class II; I-Ealpha; major histocompatibility complex H-2E beta chain; MGC117888; MHC class II antigen E alpha; MHC class II IE-b; MHC class II protein; MHC H2-IE-beta cell surface glycoprotein | |
| Mouse | |
| Protein G | |
| RUO | |
| 100504404, 14969 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
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