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Invitrogen™ HVCN1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Marca: Invitrogen™ PA521008
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Descripción
A suggested positive control is human spleen tissue lysate. PA5-21008 can be used with blocking peptide PEP-1122.
HVCN1 (hydrogen voltage-gated channel 1), a voltage gated proton channel protein that is highly expressed in immune tissues, mediates the proton conductances required by phagocytic leukocytes for the oxidative burst that underlies microbial killing. HVCN1 moderates the voltage-dependent proton permeability of excitable membranes by allowing the flow of protons in accordance to their electrochemical gradient. HVCN1 is sensitive to zinc ions, and can be inhibited by them. HVCN1 may represent a new therapeutic target for B cell malignancies on continued signaling via the B cell antigen receptor.
Especificaciones
| HVCN1 | |
| Polyclonal | |
| Unconjugated | |
| HVCN1 | |
| 0610039P13Rik; AI450555; BTS; HV1; Hvcn1; hydrogen voltage gated channel 1; hydrogen voltage-gated channel 1; mVSOP; RGD1310788; UNQ578/PRO1140; Voltage sensor domain-only protein; voltage-gated hydrogen channel 1; Vsop; Vsop. | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 304485, 74096, 84329 | |
| Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C | |
| Liquid |
| Immunohistochemistry, Western Blot, Immunocytochemistry | |
| 1 mg/mL | |
| PBS with 0.02% sodium azide | |
| Q3U2S8, Q96D96 | |
| HVCN1 | |
| A 17 amino acid peptide near the carboxy terminus of human HVCN1. | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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