Invitrogen™ Human Serpin A3/Alpha-1-Antichymotrypsin ELISA Kit

Descripción

Human Serpin A3/Alpha-1-Antichymotrypsin quantitates human Serpin A3/Alpha-1-Antichymotrypsin in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Serpin A3/Alpha-1-Antichymotrypsin.

SERPINA encodes Alpha 1-ACT. It is an early-stage acute-phase plasma protein and a serpin that preferentially inactivates chymotrypsin, cathepsin G, and chymase. Alpha-1-ACT, a serine protease inhibitor, is tightly associated with amyloid plaques in Alzheimer's disease (AD) and in normal aged human and monkey brain. Regulation of the serine proteases and serine protease inhibitors plays an important role in neuromuscular differentiation. Prostate specific antigen (PSA), a chymotrypsin-like serine protease, is predominantly complexed to Alpha-1-ACT.