Invitrogen™ Human CRTAC1 ELISA Kit

Descripción

Human CRTAC1 quantitates human CRTAC1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human CRTAC1.

CRTAC1 encodes a glycosylated extracellular matrix protein that is found in the interterritorial matrix of articular deep zone cartilage. This protein is used as a marker to distinguish chondrocytes from osteoblasts and mesenchymal stem cells in culture. The presence of FG-GAP motifs and an RGD integrin-binding motif suggests that this protein may be involved in cell-cell or cell-matrix interactions. Copy number alterations in this gene have been observed in neurofibromatosis type 1-associated glomus tumors. Alternative splicing results in multiple transcript variants.