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Descripción
Peroxisomal multifunctional enzyme type 2 is a protein that in humans is encoded by the HSD17B4 gene. The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Especificaciones
Especificaciones
| Antígeno | HSD17B4 |
| Aplicaciones | Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot |
| Clasificación | Polyclonal |
| Concentración | 0.23 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| génica | HSD17B4 |
| N.º de referencia del gen | P51659, P51660, P97852 |
| Alias de gen | 17 beta HSD 4, D bifunctional protein, DBP, EDH17B4, HSD17B4, MFE 2, SDR8C1 |
| Símbolos de los genes | Hsd17b4 |
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Título del producto
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