missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Invitrogen™ HRK Polyclonal Antibody
Rabbit Polyclonal Antibody
Marca: Invitrogen™ PA5107146
Este artículo no se puede devolver.
Vea la política de devoluciones
Descripción
Sequence homology: Cow: 100%; Dog: 100%; Human: 100%; Mouse: 83%; Rabbit: 100%; Rat: 83%.
Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Hrk, a pro-apoptotic member of the Bcl-2 homology domain-3 (BH3)-only group of the Bcl-2 family of proteins, was also identified as novel protein induced during programmed neuronal death. It lacks significant homology to other Bcl-2 family members except for an 8-amino acid region that is similar to the BH3 motif of Bik. Hrk regulates apoptosis through interaction with the anti-apoptotic proteins Bcl-2 and Bcl-XL via this domain. It does not interact with the pro-apoptotic proteins Bax, Bak, or Bcl-XS. Hrk localizes to mitochondrial membranes in a pattern similar to that previously reported for Bcl-2 and Bcl-XL.
Especificaciones
| HRK | |
| Polyclonal | |
| Unconjugated | |
| HRK | |
| Activator of apoptosis harakiri; activator of apoptosis Hrk; AI838259; BCL2-interacting protein; BH3 interacting (with BCL2 family) domain, apoptosis agonist; BH3-interacting domain-containing protein 3; Bid3; death protein 5; DP5; harakiri; harakiri, BCL2 interacting protein; harakiri, BCL2 interacting protein (contains only BH3 domain); Hrk; Neuronal death protein DP5 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 8739 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Western Blot | |
| 0.5 mg/mL | |
| PBS with 2% sucrose and 0.09% sodium azide; pH 7.4 | |
| O00198 | |
| HRK | |
| Synthetic peptide directed towards the N terminal region of human HRK (aa 1-51). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
Corrección del contenido de un producto
Proporcione sus comentarios sobre el contenido del producto rellenando el siguiente formulario.
Título del producto
¿Detecta una oportunidad de mejora?Comparta una corrección de contenido