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Invitrogen™ HMGCR Monoclonal Antibody (CL0259)

Descripción
Immunogen sequence: HIPAYKLETL METHERGVSI RRQLLSKKLS EPSSLQYLPY RDYNYSLVMG ACCENVIGYM PIPVGVAGPL CLDEKEFQVP MATTEGCLVA Highest antigen sequence indentity to the following orthologs: Mouse - 96%, Rat - 96%.
3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) is a key enzyme in the mevalonate pathway, which is critical for the biosynthesis of cholesterol and other isoprenoids. HMGCR catalyzes the conversion of HMG-CoA to mevalonate, a rate-limiting step in the production of cholesterol. Due to its central role in cholesterol synthesis, HMGCR is a primary target for statin drugs, which are used to lower cholesterol levels and reduce the risk of cardiovascular disease.
Especificaciones
Especificaciones
| Antígeno | HMGCR |
| Aplicaciones | Immunohistochemistry (Paraffin), Western Blot |
| Clasificación | Monoclonal |
| Clon | CL0259 |
| Concentración | 0.6 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| génica | HMGCR |
| N.º de referencia del gen | P04035 |
| Alias de gen | 3H3M; 3-hydroxy-3-methylglutaryl CoA reductase (NADPH); 3-hydroxy-3-methylglutaryl-CoA reductase; 3-hydroxy-3-methylglutaryl-Coenzyme A reductase; HMDH; HMG CoA reductase; HMG CoAR; HMG-CoA reductase; HMG-CoAR; HMGCR; hydroxymethylglutaryl-CoA reductase; LDLCQ3; MGC103269; Red |
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Título del producto
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