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Invitrogen™ HLA-ABCE Monoclonal Antibody (TP25.99SF), Alexa Fluor™ 488
Mouse Monoclonal Antibody
Marca: Invitrogen™ MA544136
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Descripción
This antibody recognizes an extracellular epitope on HLA-ABC and HLA-E molecules, but not HLA-G. It can be used for discrimination between HLA-G and other HLA-class I antigens.
HLA-A, -B, and -C are major histocompatibility complex (MHC)-class I antigens. Like other class I molecules (i.e. HLA-E, -F, -G), HLA-A, -B, and -C are heterodimers consisting of a 40 - 45 kDa transmembrane glycoproteic alpha-chain, noncovalently combined to the invariant B2-microglobulin. HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.
Especificaciones
| HLA-ABCE | |
| Monoclonal | |
| 0.1 mg/mL | |
| PBS with 0.2% BSA and 15mM sodium azide | |
| P01889, P04439, P10321, P13747 | |
| HLA-A, HLA-B, HLA-C, HLA-E | |
| IFN-gamma-treated human melanoma cells Colo 38. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Flow Cytometry, Western Blot | |
| TP25.99SF | |
| Alexa Fluor 488 | |
| HLA-E | |
| PBS with 0.2% BSA and 15mM sodium azide; pH 7.4 | |
| Mouse | |
| Size-exclusion chromatography | |
| RUO | |
| 3105, 3106, 3107, 3133 | |
| 4°C, store in dark, DO NOT FREEZE! | |
| Liquid |
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