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Descripción
The antibody is specific to HIP1.
The product of this gene is a membrane-associated protein that colocalizes with huntingtin. This protein has similarities to cytoskeleton proteins and its interaction with huntingtin is thought to play a functional role in the cell filament network. Loss of normal huntingtin-HIP1 interaction in Huntington disease may contribute to a defect in membrane-cytoskeletal integrity in the brain. This gene could help in the understanding of the normal function of huntingtin and also the pathogenesis of Huntington disease. It also has been implicated in the pathogenesis of hematopoietic maligcies. An alternative splice variant of this gene has been described but its full length sequence has not been determined.
Especificaciones
Especificaciones
| Antígeno | HIP1 |
| Aplicaciones | Immunohistochemistry (Paraffin), Western Blot, Immunoprecipitation |
| Clasificación | Polyclonal |
| Concentración | 0.13 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| génica | HIP1 |
| N.º de referencia del gen | O00291, Q8VD75 |
| Alias de gen | HIP 1, HIP I, HIP1, ILWEQ |
| Símbolos de los genes | Hip1 |
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Título del producto
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