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Invitrogen™ HGF Polyclonal Antibody
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Product Code. 10617050
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Cantidad:
400 μL
Unit Size:
100 microgramos
Product Code. Cantidad unitSize
10617050 400 μL 100 microgramos
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Product Code. 10617050

Brand: Invitrogen™ PA511725

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Description

Rabbit Polyclonal Antibody

HGF Polyclonal Antibody for Western Blot, IHC (P), Flow

Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms.
TRUSTED_SUSTAINABILITY

Specifications

Antígeno HGF
Aplicaciones Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Clasificación Polyclonal
Concentración 2.0 mg/mL
Conjugado Unconjugated
Formulación PBS with 0.09% sodium azide; pH 7.4
génica Hgf
N.º de referencia del gen P14210
Alias de gen C230052L06Rik; DFNB39; Fibroblast derived tumor cytotoxic factor; fibroblast-derived tumor cytotoxic factor; F-TCF; hepatocyte growth factor; Hepatocyte growth factor (hepapoietin A; hepatocyte growth factor (hepapoietin A; scatter factor); Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain; Hepatopoeitin A; hepatopoeitin-A; HepatopoietinA; hepatopoietin-A; Hgf; HGF/SF; HGFB; HPTA; Lung fibroblast derived mitogen; lung fibroblast-derived mitogen; NK1; NK2; Scatter factor; scatter factor); SF; SF/HGF
Símbolos de los genes Hgf
Especie del huésped Rabbit
Inmunógeno KLH conjugated synthetic peptide between 521-554 amino acids from the C-terminal region of human HGF.
Método de purificación Size-exclusion - Dialysis, Ammonium sulfate precipitation
Cantidad 400 μL
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 3082
Especies diana Human
Contenido y almacenamiento Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Tipo de producto Antibody
Formulario Liquid
Isotype IgG
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