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Invitrogen™ HDAC1 Monoclonal Antibody (E31), Invitrogen™

Mouse Monoclonal Antibody
Marca: Invitrogen™ MA551103
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Descripción
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. HDAC1 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, HDAC1 deacetylates p53 and modulates its effect on cell growth and apoptosis.
Especificaciones
| HDAC1 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.05% Proclin 300; pH 7.4 | |
| Q13547 | |
| HDAC1 | |
| Recombinant Human HDAC1 protein, Met1-Ala482 (Accession #Q13547). | |
| 200 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG2b κ |
| Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| E31 | |
| Unconjugated | |
| HDAC1 | |
| DKFZp686H12203; GON-10; HD1; Hdac1; Hdac1-ps; Histone deacetylase 1; histone deacetylase 1-like protein; MommeD5; reduced potassium dependency, yeast homolog-like 1; RP4-811H24.2; RPD3; RPD3L1 | |
| Mouse | |
| Protein A/G | |
| RUO | |
| 3065 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
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