missing translation for 'onlineSavingsMsg'
Learn More
Learn More
KLRG1 Hamster anti-Mouse, BUV395, Clone: 2F1, BD Optibuild™
Hamster Monoclonal Antibody
Marca: BD Biosciences 740279
Este artículo no se puede devolver.
Vea la política de devoluciones
Descripción
The 2F1 monoclonal antibody specifically binds to KLRG1 ( K iller cell L ectin-like R eceptor mmunoreceptor T yrosine-based I nhibitory M otif); its ligand has not been identified KLRG1 is expressed mainly as a homodimeric molecule consisting of two N-glycosylated subunits of approximately 30-38 kDa. The level of KLRG1 expression is reduced in MHC class I-deficient mice, although direct binding of KLRG1 to MHC class I antigens could not be detected. Crosslinking of KLRG1 by 2F1 mAb reduces TCR-mediated Ca++ mobiliza tion and cytotoxic responses (but not IFN-γproduction) by CD8+ T cells and inhibits IFN-γand TNF production and redirected lysis by NK cells.
Especificaciones
| KLRG1 | |
| Monoclonal | |
| 0.2mg/mL | |
| Klrg1; Killer cell lectin-like receptor subfamily G member 1; MAFA; 2F1 Ag | |
| Hamster | |
| Affinity Purified | |
| RUO | |
| Mouse | |
| IgG2 κ |
| Flow Cytometry | |
| 2F1 | |
| Brilliant Ultraviolet 395 | |
| Aqueous buffered solution containing ≤0.09% sodium azide. | |
| A-LAK from C57BL/6 mice | |
| 50 μg | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
Corrección del contenido de un producto
Proporcione sus comentarios sobre el contenido del producto rellenando el siguiente formulario.
Título del producto
For Research Use Only
¿Detecta una oportunidad de mejora?Comparta una corrección de contenido