missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Anticuerpos
  4. Anticuerpos primarios
  5. Todos los anticuerpos primarios
  6. 13424509

Invitrogen™ GPR68 Polyclonal Antibody

Código de producto. 13424509
Change view
Click to view available options
Cantidad:
50 μg
missing translation for 'unitSize'
50 microgramos
Product Code. Cantidad unitSize
13424509 50 μg 50 microgramos
1 missing translation for 'options'
This item is not returnable. View return policy

Product Code. 13424509

missing translation for 'mfr': Invitrogen™ PA532836

Por favor, para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo.

This item is not returnable. View return policy

Description

Rabbit Polyclonal Antibody

Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Rat (100%); Mouse, Bat, Dog, Hamster, Panda, Horse, Pig (94%); Bovine, Rabbit, Platypus (89%); Elephant (83%). For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

GPR68 (also known as OGR1 - ovarian cancer G-protein coupled receptor 1) is a proton-sensing receptor involved in pH homeostasis. It represents an osteoblastic pH sensor regulating the cell-mediated response to acidosis in bone. GPR68 mediates its action by association with G proteins that stimulate inositol phosphate (IP) production or CA2+ mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Also found to serve as a tumor suppressor in prostate cancer. Mutations to the gene result in amelogenesis imperfecta, hypomaturation type 2A6.
TRUSTED_SUSTAINABILITY

Specifications

Antígeno GPR68
Aplicaciones ELISA, Immunohistochemistry (Paraffin)
Clasificación Polyclonal
Concentración 1 mg/mL
Conjugado Unconjugated
Formulación PBS with 0.1% sodium azide
génica GPR68
N.º de referencia del gen Q15743
Alias de gen BB131428; Brgr1; Brgrb; G protein-coupled receptor 68; GPR12A; Gpr68; G-protein coupled receptor 68; Ogr1; OGR-1; ovarian cancer G protein-coupled receptor, 1; ovarian cancer G-protein coupled receptor 1; Sphingosylphosphorylcholine receptor
Símbolos de los genes GPR68
Especie del huésped Rabbit
Inmunógeno Synthetic 18 amino acid peptide from 1st extracellular domain of human GPR68.
Método de purificación Antigen affinity chromatography
Cantidad 50 μg
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 314386, 8111
Especies diana Human, Rat, Monkey
Contenido y almacenamiento Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Tipo de producto Antibody
Formulario Liquid
Isotype IgG
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.