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DCX, Goat, Polyclonal Antibody, Abnova™
Goat polyclonal antibody raised against synthetic peptide of DCX.
Marca: Abnova PAB19645.100ug
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Descripción
In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The protein encoded by this gene is a cytoplasmic protein which appears to direct neuronal migration by regulating the organization and stability of microtubules. The encoded protein contains two doublecortin domains, which bind microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene are a cause of X-linked lissencephaly. Multiple transcript variants encoding at least three different isoforms have been found for this gene. [provided by RefSeq
Sequence: C-KTSANMKAPQSEspecificaciones
| DCX | |
| Polyclonal | |
| Goat polyclonal antibody raised against synthetic peptide of DCX. | |
| In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide) | |
| NP_000546.2;NP_835365.1;NP_835364.1;NP_001182482.1 | |
| DCX | |
| A synthetic peptide corresponding to amino acids 232-242 at internal region of human DCX. | |
| 100 μg | |
| Primary | |
| This antibody is expected to recognize all four reported isoforms (NP_000546.2; NP_835365.1; NP_835364.1; NP_001182482.1). Reported variants represent identical protein: NP_835364.1 and NP_835366.1. | |
| Store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| ELISA, Western Blot | |
| Unconjugated | |
| ELISA (1:32000) Western Blot (0.01-0.03 ug/mL) The optimal working dilution should be determined by the end user. | |
| DCX | |
| DBCN/DC/LISX/SCLH/XLIS | |
| Goat | |
| Antigen affinity purification | |
| RUO | |
| 1641 | |
| Human | |
| Liquid |
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Título del producto
For Research Use Only
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