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PeproTech GM-CSF Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™
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Código de producto. 17865083
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Cantidad:
2 x 500 μg
25 μg
50 μg
500 μg
Tamaño de la unidad:
1 miligramo
25 microgramos
50 microgramos
500 microgramos
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Código de producto. Cantidad unitSize
17865083 25 μg 25 microgramos
17854913 50 μg 50 microgramos
17805013 2 x 500 μg 1 miligramo
30054573 500 μg 500 microgramos
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Código de producto. 17865083 Proveedor PeproTech N.º de proveedor 500P225BT25UG

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Descripción

Rabbit Polyclonal Antibody

AA Sequence of recombinant protein: MAPTRSPNPV TRPWKHVDAI KEALSLLNDM RALENEKNED VDIISNEFSI QRPTCVQTRL KLYKQGLRGN LTKLNGALTM IASHYQTNCP PTPETDCEIE VTTFEDFIKN LKGFLFDIPF DCWKPVQK. Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Rat GM-CSF. Anti-Rat GM-CSF-specific antibody was purified by affinity chromatography and then biotinylated. Sandwich ELISA: To detect Rat GM-CSF by sandwich ELISA (using 100 mL/well) a concentration of 0.25-1.0 μg/mL of this antibody is required. This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti- Rat GM-CSF (500-P225) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Rat GM-CSF. Western Blot: To detect Rat GM-CSF by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 mg/mL. When used in conjunction with compatible development reagents the detection limit for Recombinant Rat GM-CSF is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions. 500-P225BT-1MG will be provided as 2 x 500 μg

The GM-CSF gene encodes for a cytokine that regulates the production, differentiation, and function of macrophages and granulocytes. The active form of the protein exists as a homodimer in the extracellular space. This gene is located in a cluster of related genes at the chromosome region 5q31, which has been associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include interleukins 4, 5, and 13. The gene is involved in promoting tissue inflammation. Elevated levels of cytokines, including the one produced by this gene, have been observed in SARS-CoV-2 infected patients with acute respiratory distress syndrome. Mice that lack this gene or its receptor have been shown to develop pulmonary alveolar proteinosis.
TRUSTED_SUSTAINABILITY

Especificaciones

Antígeno GM-CSF
Aplicaciones ELISA, Western Blot
Clasificación Polyclonal
Concentración 0.1-1.0 mg/mL
Conjugado Biotin
Formulación PBS with no preservative
génica CSF2
N.º de referencia del gen P48750
Alias de gen colony stimulating factor 2; colony stimulating factor 2 (granulocyte-macrophage); colony-stimulating factor; CSF; CSF2; Csfgm; cytokine; GMCSF; Gm-CSf; granulocyte macrophage colony stimulating factor; granulocyte macrophage-colony stimulating factor; granulocyte-macrophage colony stimulating factor 2; granulocyte-macrophage colony-stimulating factor; MGC131935; MGC138897; MGC151255; MGC151257; MGI-IGM; M-GM-CSF; molgramostin; put. GM-CSF; sargramostim
Símbolos de los genes CSF2
Especie del huésped Rabbit
Inmunógeno E.coli-derived Recombinant Rat GM-CSF.
Método de purificación Antigen affinity chromatography
Cantidad 25 μg
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 116630
Especies diana Rat
Contenido y almacenamiento -20°C
Tipo de producto Antibody
Formulario Lyophilized
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