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Invitrogen™ GLP-1 Monoclonal Antibody (10)
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Código de producto. 11524142
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Cantidad:
400 μL
Tamaño de la unidad:
200 microlitros
Código de producto. Cantidad unitSize
11524142 400 μL 200 microlitros
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Código de producto. 11524142

Marca: Invitrogen™ ABS0331002

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Descripción

Mouse Monoclonal Antibody

ABS 033-10-02 detects the amidated N-terminus of GLP-1(7-37) and GLP-1(7-36) in human samples. ABS 033-10-02 has been successfully used in ELISA procedures. ABS 033-10-02 binds the free N-terminus of GLP-1(7-37) and GLP-1(7-36)amide and shows <0.2% cross-reactivity with GLP-1(9-36)amide, glucagon and human GIP. Cross-reacts 0.25% with GLP-1(1-37), approximately 6% with human GLP-2 and approximately 50% with exendin-4. NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL.

GCG is also known as GLP1, or Glucagon. Glucagon is a 29-amino acid pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis.It is mapped to 2q36-2q37. GLP1, also known as 7-37 for the codons of the preproglucagon molecule which encode it, renders pancreatic beta-cells 'glucose-competent' and may be useful in the treatment of noninsulin-dependent diabetes mellitus. Also, GLP1 is a potent insulin secretagogue.It plays a major role in the enteroinsular axis, accounting, for example, for the finding that plasma insulin levels accompanying oral intake of glucose are greater than those observed when glucose is given intravenously.
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Especificaciones

Antígeno GLP-1
Aplicaciones ELISA
Clasificación Monoclonal
Clon 10
Concentración 1.00 mg/mL
Conjugado Unconjugated
Formulación PBS with 15mM sodium azide; pH 7.4
génica GCG
N.º de referencia del gen P01275
Alias de gen GCG; Glicentin; Glicentin-related polypeptide; GLP1; GLP-1; GLP-1(7-36); GLP-1(7-37); GLP1/2; GLP2; GLP-2; Glu; glucagon; Glucagon like peptide 1; Glucagon-like peptide 1; Glucagon-like peptide 1(7-36); Glucagon-like peptide 1(7-37); Glucagon-like peptide 2; glucagon-like peptide-1; GRPP; Incretin hormone; MGC138331; OXM; OXY; Oxyntomodulin; PPG; preproglucagon
Símbolos de los genes GCG
Especie del huésped Mouse
Inmunógeno Synthetic glucagon-like peptide-1 (7-17) adsorbed into aluminum hydroxide gel.
Método de purificación Protein A
Cantidad 400 μL
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 2641
Especies diana Human
Contenido y almacenamiento 4°C, store in dark
Tipo de producto Antibody
Formulario Liquid
Isotype IgG2a κ
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