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Invitrogen™ GHSR Polyclonal Antibody
Rabbit Polyclonal Antibody
Marca: Invitrogen™ PA528752
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Descripción
Recommended positive controls: NT2D1, PC-3, U87-MG, SK-N-SH, mouse hypothalamus, mouse brain, rat brain. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Growth hormone secretagogue receptor 1a (GHSR) is a member of the G-protein coupled receptor family. GHSR may play a role in energy homeostasis and regulation of body weight. Two identified transcript variants are expressed in several tissues and are evolutionary conserved in fish and swine. One transcript, 1a, excises an intron and encodes the functional protein; this protein is the receptor for the Ghrelin ligand and defines a neuroendocrine pathway for growth hormone release. The second transcript (1b) retains the intron and does not function as a receptor for Ghrelin; however, it may function to attenuate activity of isoform 1a. Mutations to the gene can cause isolated partial growth hormone deficiency.
Especificaciones
| GHSR | |
| Polyclonal | |
| Unconjugated | |
| Ghsr | |
| C530020I22Rik; GHDP; GH-releasing peptide receptor; Ghrelin receptor; GHRP; Ghrp receptor; GHS receptor; GHSR; GHS-R; G-protein coupled receptor; growth hormone secretagogue receptor; growth hormone secretagogue receptor type 1 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 208188, 2693 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 1 mg/mL | |
| 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7 | |
| Q92847, Q99P50 | |
| Ghsr | |
| Synthetic peptide encompassing a sequence within the Extracellular domain of human GHS-R1. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
Título del producto
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