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Invitrogen™ GFI1 Polyclonal Antibody
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Código de producto. 13267368
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Cantidad:
100 μg
Tamaño de la unidad:
100 microgramos
Código de producto. Cantidad unitSize
13267368 100 μg 100 microgramos
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Codice prodotto. 13267368

Marca: Invitrogen™ PA523495

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Descrizione

Rabbit Polyclonal Antibody

GFI1 Polyclonal Antibody for Western Blot, IHC (P)

GFI1 is a nuclear zinc finger (ZF) transcriptional repressor that plays an important role in hematopoiesis and inner ear development, and has been implicated in lymphomagenesis. The Gfi1 protein expression is regulated by the ubiquitin-proteasome system. It is reported that ubiquitin ligase Triad1 interacts with the DNA-binding domain of Gfi-1. Gfi-1 represses transcription by directly binding to the consensus DNA sequence in the promoters of its target genes. Deficiency of Gfi-1 causes neutropenia and an accumulation of granulomonocytic precursor cells that is reminiscent of a myelodysplastic syndrome in mice.
TRUSTED_SUSTAINABILITY

Specifica

Antígeno GFI1
Aplicaciones Immunohistochemistry (Paraffin), Western Blot
Clasificación Polyclonal
Concentración 1 mg/mL
Conjugado Unconjugated
Formulación PBS with 0.05% sodium azide
génica GFI1
N.º de referencia del gen P70338, Q07120, Q99684
Alias de gen AW495828; FLJ94509; Gfi1; GFI-1; GFI1A; growth factor independence-1; growth factor independent 1; growth factor independent 1 transcription repressor; growth factor independent 1 transcriptional repressor; growth factor independent protein 1; Growth factor independent-1; Pal1; Pal-1; SCN2; Zinc finger protein 163; zinc finger protein Gfi-1; ZNF163
Símbolos de los genes GFI1
Especie del huésped Rabbit
Inmunógeno A portion of amino acid 280-330 of human Zinc finger protein Gfi-1.
Método de purificación Protein A
Cantidad 100 μg
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 100139952, 14581, 24388, 2672, 429088
Especies diana Human, Mouse, Rat, Bovine, Chicken
Contenido y almacenamiento Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Tipo de producto Antibody
Formulario Liquid
Isotype IgG
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