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GFAP (Glial Fibrillary Acidic Protein) Mouse, anti-Human, Unconjugated, Clone: 2E1.E9, STEMCELL Technologies
Mouse Monoclonal Antibody
Marca: Stemcell Technologies 60048
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Descripción
- The 2E1.E9 antibody reacts with glial fibrillary acidic protein (GFAP), an ∼49 kDa type III intermediate filament (IF) protein that, within the central nervous system, is expressed primarily by astrocytes, though found at high levels in some glial-derived tumors
- GFAP is thought to contribute to the structural architecture and strength of the cytoskeleton
- The 2E1.E9 antibody does not cross-react with other IF proteins and can be used to distinguish astrocytes from other glial cells
- GFAP has also been identified in Leydig cells, keratinocytes, chondrocytes and osteocytes
- Many mutations in the GFAP gene (>50) have been associated with Alexander disease, a progressive leukoencephalopathy characterized by cytoplasmic inclusions and dysfunctional myelination
- This antibody clone has been verified for labeling neural stem and progenitor cells grown in NeuroCult™ NS-A Proliferation Kit (Human; Catalog #05751) and NeuroCult™ Proliferation Kit (Mouse; Catalog #05702)
Especificaciones
| GFAP (Glial Fibrillary Acidic Protein) | |
| Monoclonal | |
| Unconjugated | |
| 100 μg | |
| Human, Rat, Mouse | |
| Astrocytes, Neural Cells, PSC-Derived |
| Immunohistochemistry, Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence | |
| 2E1.E9 | |
| Mouse | |
| Primary | |
| IgG2b |
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