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Invitrogen™ GEF-H1 Monoclonal Antibody (GT336)
Mouse Monoclonal Antibody
Marca: Invitrogen™ MA527803
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Descripción
Positive Control: 293T, A431, HeLa, C8D30, BCL-1, Raw264.7, C2C12, Rat-2, 3A6 Predicted Reactivity: Dog (92%), Pig (96%), Bovine (94%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
GEF-H1 activates Rho GTPases by promoting the exchange of GDP and GTP. Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. GEF-H1 may be involved in epithelial barrier permeability, cell motility and polarization, dendritic spine morphology, antigen presentation, leukemic cell differentiation, cell cycle regulation, innate immune response, and cancer. Alternatively spliced transcript variants encoding different isoforms have been identified.
Especificaciones
| GEF-H1 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with no preservative | |
| Q5FVC2, Q60875, Q92974 | |
| ARHGEF2 | |
| Recombinant protein encompassing a sequence within the C-terminus region of human GEF-H1. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG1 |
| Western Blot, Immunocytochemistry | |
| GT336 | |
| Unconjugated | |
| ARHGEF2 | |
| AA408978; ARHGEF2; CG10188; CG10188-PA; CG10188-PB; CG10188-PC; cyst; cyst-PA; cyst-PB; cyst-PC; cysts; DKFZp547L106; DKFZp547P1516; Dmel\CG10188; Dmel_CG10188; FLJ45440; GEF; GEFH1; GEF-H1; Guanine nucleotide exchange factor H1; Kiaa0651; Lbcl1; LBC'S first cousin; Lfc; LFP40; Lymphoid blast crisis-like 1; microtubule-regulated Rho-GEF; mKIAA0651; oncogene LFC; OTTHUMP00000018855; P40; Proliferating cell nucleolar antigen p40; rho guanine nucleotide exchange factor 2; rho guanine nucleotide exchange factor 2-like protein; Rho/Rac guanine nucleotide exchange factor (GEF) 2; Rho/Rac guanine nucleotide exchange factor 2; rhobin | |
| Mouse | |
| Protein G | |
| RUO | |
| 16800, 310635, 9181 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
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