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Invitrogen™ GDF15 Polyclonal Antibody

Descripción
GDF15 Polyclonal Antibody for ICC/IF, Western Blot
GDF-15 belongs to the TGF-beta cytokine family, whose members play an important role during prenatal development and postnatal growth, and the remodeling and maintenance of a variety of tissues and organs. GDF-15 is expressed predominantly in the placenta and, to a much lesser extent, in various other tissues. The presence of GDF-15 in amniotic fluid and its elevated levels in the sera of pregnant women suggest GDF-15's involvement in gestation and embryonic development. GDF-15 generally exerts tumor suppressive activities and is one of the predominant factors produced and secreted in response to activation of the p53 pathway. Interestingly, the serum level of GDF-15 is positively correlated with neoplastic progression of several tumor types, including certain colorectal, pancreatic, and prostate cancers.
Especificaciones
Especificaciones
| Antígeno | GDF15 |
| Aplicaciones | Western Blot, Immunocytochemistry |
| Clasificación | Polyclonal |
| Concentración | 0.25 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 0.1% sodium azide; pH 7.4 |
| génica | Gdf15 |
| N.º de referencia del gen | Q99988 |
| Alias de gen | Gdf15; GDF-15; growth differentiation factor 15; growth/differentiation factor 15; macrophage inhibiting cytokine-1; macrophage inhibitory cytokine 1; MIC1; MIC-1; NAG1; NAG-1; NRG-1; NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1; NSAID-activated gene 1 protein; NSAID-regulated gene 1 protein; PDF; PLAB; Placental bone morphogenetic protein; placental TGF-beta; Prostate differentiation factor; PTGFB; PTGF-beta; SBF |
| Símbolos de los genes | Gdf15 |
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Título del producto
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