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Invitrogen™ FZD8 Recombinant Rabbit Monoclonal Antibody (JB40-16)

Descripción
Positive Control: Mouse lung tissue lysates, Human kidney tissue, human uterus tissue.
Members of the Frizzled family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Frizzled 8 is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. Its expression has been reported in brain, heart, kidney, pancreas, and skeletal muscle. ESTs have been isolated from embryo, eye, head/neck, heart, kidney, liver/spleen, pancreas, prostate, and testis libraries, as well as many tumor libraries. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.
Especificaciones
Especificaciones
| Antígeno | FZD8 |
| Aplicaciones | Immunohistochemistry (Paraffin), Western Blot |
| Clasificación | Recombinant Monoclonal |
| Clon | JB40-16 |
| Concentración | 1 mg/mL |
| Conjugado | Unconjugated |
| Formulación | TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4 |
| génica | Fzd8 |
| N.º de referencia del gen | Q9H461 |
| Alias de gen | frizzled 8, seven transmembrane spanning receptor; frizzled class receptor 8; frizzled family receptor 8; frizzled homolog 8; frizzled homolog 8 (Drosophila); frizzled-8; Fz8; Fz-8; Fzd8; hFZ8; HGNC:4046 |
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Título del producto
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