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Invitrogen™ Fumarase Polyclonal Antibody
Descripción
Recommended positive controls: 293T, A431, mosue liver, rat liver. Predicted reactivity: Rat (96%), Zebrafish (86%), Pig (97%), Chicken (89%), Sheep (97%), Chimpanzee (99%), Bovine (96%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene is an enzymatic component of the tricarboxylic acid cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy.
Especificaciones
Especificaciones
| Antígeno | Fumarase |
| Aplicaciones | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Clasificación | Polyclonal |
| Concentración | 1 mg/mL |
| Conjugado | Unconjugated |
| Formulación | 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7 |
| génica | FH |
| N.º de referencia del gen | P07954, P14408, P97807 |
| Alias de gen | EF-3; Fh; Fh1; Fh-1; FMRD; fumarase; fumarate hydratase; fumarate hydratase 1; fumarate hydratase, mitochondrial; HLRCC; LRCC; MCL; MCUL1 |
| Símbolos de los genes | FH, Fh1 |
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Título del producto
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