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Invitrogen™ FTO Polyclonal Antibody
Rabbit Polyclonal Antibody
Marca: Invitrogen™ PA585698
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Beschreibung
Keep as concentrated solution. Predicted reactivity: Mouse (83%), Rat (83%), Pig (85%), Rabbit (88%). Positive Control: U87-MG, SK-N-SH, IMR32, SK-N-AS, 293T, HepG2. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
FTO is a novel protein and a member of the non-heme dioxygenase (Fe(II)-and 2-oxoglutarate-dependent dioxygenases) superfamily. Amino acid conservation patterns support this hypothesis and indicates that both 2-oxoglutarate and iron should be important for FTO function. Though not much is yet known about FTO, it is thought that the protein may somehow modify the activity of genes involved in metabolism and fat storage, which in turn may influence a person's risk of obesity.
Spezifikation
| FTO | |
| Polyclonal | |
| Unconjugated | |
| Fto | |
| AlkB homolog 9; ALKBH9; alpha-ketoglutarate-dependent dioxygenase FTO; AW743446; BMIQ14; fat mass and obesity associated; fat mass and obesity-associated protein; fatso; FTO; GDFD; KIAA1752; m6A(m)-demethylase FTO; MGC5149; mKIAA1752; mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; mRNA N(6)-methyladenosine demethylase FTO; Protein fatso; protein fto; RGD1305121; tRNA N1-methyl adenine demethylase FTO; U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 291905, 79068 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Western Blot, Immunocytochemistry | |
| 2.05 mg/mL | |
| PBS with 20% glycerol and 0.025% ProClin 300; pH 7 | |
| Q2A121, Q9C0B1 | |
| Fto | |
| Recombinant protein encompassing a sequence within the center region of human FTO. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Human, Rat | |
| Antibody | |
| IgG |
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