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Invitrogen™ FOLR2 Monoclonal Antibody (OTI4G6)
Beschreibung
FOLR2 Monoclonal Antibody for IHC (P), Western Blot
FOLR2 is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients.
Spezifikation
Spezifikation
| Antígeno | FOLR2 |
| Aplicaciones | Immunohistochemistry (Paraffin), Western Blot |
| Clasificación | Monoclonal |
| Clon | OTI4G6 |
| Concentración | 1 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3 |
| génica | FOLR2 |
| N.º de referencia del gen | P14207 |
| Alias de gen | BETA-HFR; FBP; FBP/PL-1; Fbp2; folate binding protein; folate binding protein 2; folate receptor 2; folate receptor 2 (fetal); folate receptor beta; folate receptor, beta; folate receptor, fetal/placental; Folate-binding protein 2; folate-binding protein, fetal/placental; Folbp2; Folbp-2; FOLR2; FR-beta; FR-P3; placental folate-binding protein |
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