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Invitrogen™ FNIP1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Marca: Invitrogen™ PA564453
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Descripción
Immunogen sequence: DHCCMLEFSK ILCTKNNKQN NEFCKCIETV PQDSCKTCFP QQDQRDTLSI LVPHGDKESS DKKIAVGTEW D Highest antigen sequence identity to the following orthologs: Mouse - 77%, Rat - 82%.
FNIP1 encodes a protein that binds to the tumor suppressor protein folliculin and to AMP-activated protein kinase (AMPK). The encoded protein participates in the regulation of cellular metabolism and nutrient sensing by modulating the AMPK and target of rapamycin signaling pathways. This gene has a closely related paralog that encodes a protein with similar binding activities. Both related proteins also associate with the molecular chaperone heat shock protein-90 (Hsp90) and negatively regulate its ATPase activity and facilitate its association with folliculin. Diseases associated with FNIP1 include Birt-Hogg-Dube Syndrome and Pleural Disease.
Especificaciones
| FNIP1 | |
| Polyclonal | |
| Unconjugated | |
| FNIP1 | |
| A730024A03Rik; AI838773; AW557298; FNIP1; folliculin interacting protein 1; folliculin-interacting protein 1; Kiaa1961 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 96459 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin) | |
| 0.1 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q8TF40 | |
| FNIP1 | |
| Recombinant protein corresponding to Human FNIP1. Recombinant protein control fragment (Product #RP-104216). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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