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Invitrogen™ FEN1 Polyclonal Antibody
Descripción
Recommended positive controls: HepG2, NIH-3T3, JC, BCL-1, Raw264.7, PC-12. Predicted reactivity: Mouse (96%), Rat (95%), Chicken (81%), Sheep (94%), Rhesus Monkey (98%), Bovine (96%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
FEN-1 (Flap Endonuclease and Five prime Exonuclease) is a 42 a protein that functions as an endonuclease that cleaves branched DNA structures containing single-stranded 5' flaps or as an exonuclease on DNA nicks and gaps. FEN-1 endonuclease and exonuclease activities are stimulated by an association with proliferating cell nuclear antigen (PCNA) in the nucleus. FEN-1 is believed to have important roles in DNA replication and repair and is required in cell-free DNA replication systems.
Especificaciones
Especificaciones
| Antígeno | FEN1 |
| Aplicaciones | Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Proximity Ligation Assay, Immunocytochemistry |
| Clasificación | Polyclonal |
| Concentración | 0.2 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7 |
| génica | FEN1 |
| N.º de referencia del gen | P39748, P39749, Q5XIP6 |
| Alias de gen | AW538437; DNase IV; fen1; FEN-1; fen1 {ECO:0000255; FEN-1 {ECO:0000255; Flap endonuclease 1; flap endonuclease 1 {ECO:0000255; flap structure specific endonuclease 1; flap structure-specific endonuclease 1; flap structure-specific endonuclease 1 {ECO:0000255; HAMAP-Rule:MF_03140}; hFEN-1; Maturation factor 1; maturation factor-1; MF1; RAD2 |
| Símbolos de los genes | FEN1 |
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Título del producto
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