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FCER2 Monoclonal Antibody (OTI1E5), TrueMAB™, OriGene
Descripción
CD23 is a 45 kDa glycoprotein which is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. The CD23 molecule is identical to the low affinity IgE receptor found on B cells. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic lymphocyctic leukaemia and some cases of centroblastic/centrocytic lymphoma. CD23 is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. Functionally, CD23 is involved in B cell growth and differentiation, and IgE production. Further, CD23 has a soluble form that is a potent mitogenic factor. Diseases associated with CD23 dysfunction include chronic conjunctivitis and chronic lymphocytic leukemia.
Especificaciones
Especificaciones
| Antígeno | FCER2 |
| Aplicaciones | Western Blot |
| Clasificación | Monoclonal |
| Clon | OTI1E5 |
| Concentración | 1 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 1% BSA, 50% glycerol and 0.02% sodium azide |
| génica | FCER2 |
| N.º de referencia del gen | P06734 |
| Alias de gen | BLAST-2, CD23, CD23A, CLEC4J, FCE2, IGEBF |
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Título del producto
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