missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Invitrogen™ FAM193B Polyclonal Antibody
Descripción
Immunogen sequence: NTVPNLSRVI WVKTPKPGYP SSEEPSSKEV PSCKQELPEP VSSGGKPQKG KRQGSQAKKS EASPAPRPPA SLEVPSAKGQ VAGPKQ Highest antigen sequence indentity to the following orthologs: Rat - 78%, Mouse - 79%.
FAM193B, also known as IRIZIO, was initially identified as a protein that is upregulated in alveolar rhabdomyosarcoma (ARMS), a type of fast-growing tumor characterized by chromosomal translocations fusing the PAX3 or PAX7 gene with that of FOXO1. It has been suggested that, in addition to the PAX3-FOXO1 gene fusion, disruption of the Rb and p53 pathways is required for full ARMS tumorigenesis. In PAX3-FOXO1-expressing primary mouse fibroblasts that possessed a defective p53 pathway, FAM193B expression enabled the tumorigenic transformation, suggesting that FAM193B may contribute to rhabdomyosarcomagenesis in humans.
Especificaciones
Especificaciones
| Antígeno | FAM193B |
| Aplicaciones | Immunocytochemistry |
| Clasificación | Polyclonal |
| Concentración | 0.1 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| génica | FAM193B |
| N.º de referencia del gen | Q96PV7 |
| Alias de gen | FAM193B; family with sequence similarity 193 member B; IRIZIO; KIAA1931; Protein FAM193B |
| Símbolos de los genes | FAM193B |
| Mostrar más |
Título del producto
Al hacer clic en Enviar, acepta que Fisher Scientific se ponga en contacto con usted en relación con los comentarios que ha proporcionado en este formulario. No compartiremos su información para ningún otro fin. Toda la información de contacto proporcionada se mantendrá de acuerdo con nuestra Política de Privacidad. Política de privacidad.
¿Detecta una oportunidad de mejora?