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  6. Factor VIII Related Antigen/von Willebrand Factor Ab-2 Mouse Monoclonal Antibody, Epredia™

Factor VIII Related Antigen/von Willebrand Factor Ab-2 Mouse Monoclonal Antibody, Epredia™

Código de producto. p-4542649 Tienda Epredia Productos
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Cantidad:
100 μL
200 μL
500 μL
1 mL
7 mL
12 mL
Formulario:
Concentrated
Prediluted
Ready-to-Use
Concentración:
1mg/mL
200μg/mL
Prediluted
Unit Size:
1 ml
100 microlitros
12 ml
200 microlitros
500 microlitros
7 ml
Product Code. Cantidad Formulario Concentración unitSize
12622147 100 μL Concentrated 200μg/mL 100 microlitros
12642147 100 μL Concentrated 1mg/mL 100 microlitros
12652147 200 μL Concentrated 1mg/mL 200 microlitros
12632147 500 μL Concentrated 200μg/mL 500 microlitros
12612147 1 mL Concentrated 200μg/mL 1 ml
12682147 7 mL Prediluted Prediluted 7 ml
12692147 12 mL Ready-to-Use Prediluted 12 ml
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Product Code. 12622147

Brand: Epredia MS722P0

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Description

Ensure accurate, reproducible results in immunohistochemistry experiments.

Factor VIII related antigen or von Willebrand factor is a multimeric glycoprotein, which binds to platelet glycoprotein Ib, glycoprotein IIb/IIIa, collagen and heparin. It is synthesized by endothelial cells and stored in the Weibel-Palade granules. It mediates platelet adhesion to injured vessel walls and serves as a carrier and stabilizer for coagulation factor VIII. von Willebrand factor is one of the most useful markers to identify endothelial (or megakaryocytic) lineage of neoplasms. As not all endothelial cells synthesize/store this molecule, about 30% of tumors of vascular origin fail to stain for factor VIII related antigen, regardless of whether they are benign or malignant. Staining for factor VIII related antigen has also been used to measure angiogenesis, an indicator of tumor recurrence.

Host Species: Mouse

Clone: F8/86

Isotype: IgG1/κ

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Partially purified von Willebrand factor from human placenta

Molecular Weight: 270 kDa

Positive Control: Blood vessels in tonsil or intestine

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
TRUSTED_SUSTAINABILITY

Specifications

Antígeno Factor VIII Related Antigen/von Willebrand Factor Ab-2
Aplicaciones Immunohistochemistry (Paraffin)
Clasificación Monoclonal
Clon F8/86
Concentración 200μg/mL
Conjugado Unconjugated
Especie del huésped Mouse
Inmunógeno Partially purified von Willebrand factor from human placenta
Cantidad 100 μL
Estado normativo IVD
Disciplina de investigación Hematopoietic
Primario o secundario Primary
Especies diana Human
Formulario Concentrated
Isotype IgG2a κ
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