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Thermo Scientific™ EZ-Link™ Maleimide-PEG4-DBCO
A sulfhydryl reactive heterobifunctional crosslinker which contains a dibenzylcyclooctyne (DBCO) group for copper-free click chemistry applications. The thiol/sulfhdryl reactive maleimide can be used to label a variety of thiol containing moieties such as free cystines in proteins, peptides, or other (bio)molecules.
214.00€ - 277.00€
Especificaciones
| Reactividad química | Azida-sulfhidrilo |
|---|---|
| Cleavable | No |
| Descripción | Maleimida-PEG4-DBCO |
| Peso molecular | 647.74 |
| Pegilado | Sí |
| Código de producto | Marca | Cantidad | Precio | Cantidad y disponibilidad | |||||
|---|---|---|---|---|---|---|---|---|---|
| Código de producto | Marca | Cantidad | Precio | Cantidad y disponibilidad | |||||
|
17611586
|
Thermo Scientific™
C20041 |
10 x 1mg |
214.00€
25 miligramos |
En stock
Inicie sesión para ver el stock |
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|
17631586
|
Thermo Scientific™
C20044 |
10 x 1mg |
277.00€
paquete de 10 |
En stock
Inicie sesión para ver el stock |
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Descripción
- A sulfhydryl reactive heterobifunctional crosslinker which contains a dibenzylcyclooctyne (DBCO) group for copper-free click chemistry applications
- The thiol/sulfhdryl reactive maleimide can be used to label a variety of thiol containing moieties such as free cystines in proteins, peptides, or other (bio)molecules
- Once a protein or (bio)molecule is DBCO labeled, it can undergo a copper-free azide-alkyne cycloaddition reaction to form a stable triazole linkage with an azide labeled coupling partner
- Can be used to create diverse conjugates with the biorthogonal coupling between an alkyne and azide (supplied separately)
- The coupling or crosslinking procedure is typically done in two steps:
- First, a protein or thiol containing molecule is labeled with a DBCO group and excess crosslinker is removed
- Second, an azide containing moiety (prepared independently) is introduced into the same system as the DBCO moiety
- Labeling occurs under biological conditions without the introduction of any additional reagents such as a copper catalyst
- Reagent readily dissolves in water-miscible solvents for dilution into aqueous reaction mixtures
Especificaciones
| Azida-sulfhidrilo | |
| Maleimida-PEG4-DBCO | |
| Sí | |
| Tras su recepción, almacenar desecado a -20 °C. | |
| Hielo húmedo | |
| Etiqueta química | |
| Maleimida, DBCO | |
| 10 x 1mg | |
| Estándar, uso único | |
| Entrecruzador |
| No | |
| 647.74 | |
| 29,7 Å | |
| No determinado | |
| EZ-Link™ No-Weigh™ | |
| Heterobifuncionales | |
| Medio (de 10 a 30 Å) | |
| DMF, DMSO | |
| No |