EPHX2 Polyclonal Antibody, Invitrogen™

Descripción

Positive test controls include: 293T, LO2, SW480, Mouse liver, Mouse kidney, Mouse heart, Rat kidney. The target is usually found in the following locations: Cytoplasm, Peroxisome. Immunogen sequence: LALPRGLLND AFQKGGPEGA TTRLMKGEIT LSQWIPLMEE NCRKCSETAK VCLPKNFSIK EIFDKAISAR KINRPMLQAA LMLRKKGFTT AILTNTWLDD RAERDGLAQL MCELKMHFDF LIESCQVGMV KPEPQIYKFL LDTLKASPSE VVFLDDIGAN LKPARDLGMV TILVQDTDTA LKELEKVTGI QLLNTPAPLP TSCNPSDMSH G

This gene encodes a member of the epoxide hydrolase family. The protein, found in both the cytosol and peroxisomes, binds to specific epoxides and converts them to the corresponding dihydrodiols. Mutations in this gene have been associated with familial hypercholesterolemia. Alternatively spliced transcript variants have been described.