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Descripción
Immunogen sequence: KRHCGYSKAF QDSDEEKMHY QNGQAPPPVF LPLHHPPGKL PEPQFYAQPH TYEEPGRAGR SFTREIEASR IHIEKIIGSG DSG Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 93%.
EPHA8 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. EPHA8 plays a role in short-range contact-mediated axonal guidance during development of the mammalian nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.
Especificaciones
Especificaciones
| Antígeno | EphA8 |
| Aplicaciones | Immunohistochemistry (Paraffin) |
| Clasificación | Polyclonal |
| Concentración | 0.2 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| génica | Epha8 |
| N.º de referencia del gen | P29322 |
| Alias de gen | AW047546; Eek; EK3; epa8; EPH- and ELK-related kinase; EPH- and ELK-related tyrosine kinase; Eph receptor A8; Epha8; EPH-like kinase 3; Ephrin type-A receptor 8; Ephrin type-A receptor 8 precursor (Tyrosine-protein kinase receptor EEK) (EPH-and ELK-related kinase); Hek3; hydroxyaryl-protein kinase; KIAA1459; mKIAA1459; protein-tyrosine kinase; tyrosine-protein kinase receptor EEK; tyrosylprotein kinase |
| Símbolos de los genes | Epha8 |
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Título del producto
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